Insights

CTEH Publications

Go in depth with the latest research and academic publications from our experts, applying new scientific advances to their work on emerging issues in the field.

Scaling factors for the extrapolation of in vivo metabolic drug clearance from in vitro data: Reaching a consensus on values of human microsomal protein and hepatocellularity per gram of liver

Author from CTEH: John Lipscomb, PhD, DABT, FATS

All Authors: Barter, ZE, Bayliss, MK, Beaune, PH, Boobis, AR, Carlile, DJ, Edwards, RJ, Houston, JB, Lake, BG, Lipscomb, JC, Pelkonen, OR, Tucker, GT and Rostami-Hodjegan, A

Publication Year: 2007

Journal: Current Drug Metabolism

High-to-low dose extrapolation: issues and approaches

Author from CTEH: John Lipscomb, PhD, DABT, FATS

All Authors: Chiu, WA, Chen, C, Hogan, K, Lipscomb, JC, Scott, CS and Subramaniam, R

Publication Year: 2007

Journal: Human Ecol Risk Assmt.

Evaluation of Physiologically Based Pharmacokinetic Models for Use in Risk Assessment

Author from CTEH: John Lipscomb, PhD, DABT, FATS

All Authors: Chiu, WA, Barton, HA, Dewoskin, RS, Schlosser, P, Thompson, CM, Sonawane, B, Lipscomb, JC and Krishnan, K

Publication Year: 2007

Journal: J App Toxicol.

Pharmacokinetic and Physiologically Based Pharmacokinetic Models in IRIS assessments. In: Lipscomb JC and Ohanian EV (eds), Toxicokinetics and Risk Assessment

Author from CTEH: John Lipscomb, PhD, DABT, FATS

All Authors: DeWoskin, RS, Lipscomb, JC and Thompson, C

Publication Year: 2007

Journal: Informa Healthcare Publishers

Mode of Action as a Determining Factor in Human Health Risk Assessment of Chemical Mixtures

Author from CTEH: John Lipscomb, PhD, DABT, FATS

All Authors: Lambert, JC and Lipscomb, JC

Publication Year: 2007

Journal: Regul Toxicol Pharmacol.

The Toxicity and Risk of Chemical Mixtures

Author from CTEH: John Lipscomb, PhD, DABT, FATS

All Authors: Lipscomb, JC, Lambert, JC, and Mumtaz, M

Publication Year: 2007

Journal: Computational Toxicology: Risk Assessment for Pharmaceutical and Environmental Chemicals

Age-Dependent Partition Coefficients for a Mixture of Volatile Organic Solvents in Sprague-Dawley Rats and Humans

Author from CTEH: John Lipscomb, PhD, DABT, FATS

All Authors: Mahle, DA, Gearhart, JM, Grigsby, C, Mattie, DR, Barton, HA, Lipscomb, JC, and Cook, RS

Publication Year: 2007

Journal: J Toxicol Envtl Health

In Vitro Metabolism of the Fungicide and Environmental Contaminant Trans-Bromuconazole and Implications for Risk Assessment

Author from CTEH: John Lipscomb, PhD, DABT, FATS

All Authors: Mazur, CS, Kenneke, JF, Tebes-Stevens, C, Okino, MS, Lipscomb, JC

Publication Year: 2007

Journal: J Toxicol Envtl Health

Considerations of Design and Data when Developing Physiologically-Based Pharmacokinetic Models In: Lipscomb JC and Ohanian EV (eds), Toxicokinetics and Risk Assessment

Author from CTEH: John Lipscomb, PhD, DABT, FATS

All Authors: Robinson, PJ, Gearhart, JM, Mahle, DA, Merrill, EA, Sterner, TR, Lipscomb, JC, and Yu, KO

Publication Year: 2007

Journal: Informa Healthcare Publishers

Predicting Age-Dependent Pharmacokinetics of Six Volatile Organic Compounds in the Rat Utilizing Physiologically-Based Pharmacokinetic Modeling

Author from CTEH: John Lipscomb, PhD, DABT, FATS

All Authors: Rodriguez, CE, Mahle, DA, Gearhart, JM, Mattie, DR, Lipscomb, JC, Cook, RS and Barton, HA

Publication Year: 2007

Journal: Toxicol Sci.

Use of Chemical Fingerprinting to Establish the Presence of Spilled Crude Oil in a Residential Area Following Hurricane Katrina, St. Bernard Parish, Louisiana

Author from CTEH: Glenn Millner, PhD

All Authors: Stout SA, Liu B, Millner GC, Hamlin D, Healey E.

Publication Year: 2007

Journal: Environmental Science & Technology

Read More