Insights

CTEH Publications

Go in depth with the latest research and academic publications from our experts, applying new scientific advances to their work on emerging issues in the field.

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Dynamic Changes in Lipids and Proteins of Maternal, Fetal, and Pup Blood and Milk during Perinatal Development in CD and Wistar Rats


Author from CTEH: Tami McMullin, PhD

All Authors: Tami S. McMullin, Ezra R. Lowe, Michael J. Bartels, Mary Sue Marty

Publication Year: 2008

Journal: Oxford Academic

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Profound Metabolic Acidosis and Oxoprolinuria after Acetaminophen Use


Author from CTEH: Michael Holland, MD, FEAPCCT, FAACT, FACOEM, FACMT, FACEP

All Authors: Michael J. Hodgman, James F. Horn, Christine M. Stork, Jeanna M. Marraffa, Michael G. Holland, Richard Cantor, and Patti M. Carmel

Publication Year: 2007

Journal: PubMed Central

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Scaling factors for the extrapolation of in vivo metabolic drug clearance from in vitro data: Reaching a consensus on values of human microsomal protein and hepatocellularity per gram of liver


Author from CTEH: John Lipscomb, PhD, DABT, FATS

All Authors: Barter, ZE, Bayliss, MK, Beaune, PH, Boobis, AR, Carlile, DJ, Edwards, RJ, Houston, JB, Lake, BG, Lipscomb, JC, Pelkonen, OR, Tucker, GT and Rostami-Hodjegan, A

Publication Year: 2007

Journal: Current Drug Metabolism

High-to-low dose extrapolation: issues and approaches


Author from CTEH: John Lipscomb, PhD, DABT, FATS

All Authors: Chiu, WA, Chen, C, Hogan, K, Lipscomb, JC, Scott, CS and Subramaniam, R

Publication Year: 2007

Journal: Human Ecol Risk Assmt.

Evaluation of Physiologically Based Pharmacokinetic Models for Use in Risk Assessment


Author from CTEH: John Lipscomb, PhD, DABT, FATS

All Authors: Chiu, WA, Barton, HA, Dewoskin, RS, Schlosser, P, Thompson, CM, Sonawane, B, Lipscomb, JC and Krishnan, K

Publication Year: 2007

Journal: J App Toxicol.

Pharmacokinetic and Physiologically Based Pharmacokinetic Models in IRIS assessments. In: Lipscomb JC and Ohanian EV (eds), Toxicokinetics and Risk Assessment


Author from CTEH: John Lipscomb, PhD, DABT, FATS

All Authors: DeWoskin, RS, Lipscomb, JC and Thompson, C

Publication Year: 2007

Journal: Informa Healthcare Publishers

Mode of Action as a Determining Factor in Human Health Risk Assessment of Chemical Mixtures


Author from CTEH: John Lipscomb, PhD, DABT, FATS

All Authors: Lambert, JC and Lipscomb, JC

Publication Year: 2007

Journal: Regul Toxicol Pharmacol.

The Toxicity and Risk of Chemical Mixtures


Author from CTEH: John Lipscomb, PhD, DABT, FATS

All Authors: Lipscomb, JC, Lambert, JC, and Mumtaz, M

Publication Year: 2007

Journal: Computational Toxicology: Risk Assessment for Pharmaceutical and Environmental Chemicals

Age-Dependent Partition Coefficients for a Mixture of Volatile Organic Solvents in Sprague-Dawley Rats and Humans


Author from CTEH: John Lipscomb, PhD, DABT, FATS

All Authors: Mahle, DA, Gearhart, JM, Grigsby, C, Mattie, DR, Barton, HA, Lipscomb, JC, and Cook, RS

Publication Year: 2007

Journal: J Toxicol Envtl Health

In Vitro Metabolism of the Fungicide and Environmental Contaminant Trans-Bromuconazole and Implications for Risk Assessment


Author from CTEH: John Lipscomb, PhD, DABT, FATS

All Authors: Mazur, CS, Kenneke, JF, Tebes-Stevens, C, Okino, MS, Lipscomb, JC

Publication Year: 2007

Journal: J Toxicol Envtl Health

Considerations of Design and Data when Developing Physiologically-Based Pharmacokinetic Models In: Lipscomb JC and Ohanian EV (eds), Toxicokinetics and Risk Assessment


Author from CTEH: John Lipscomb, PhD, DABT, FATS

All Authors: Robinson, PJ, Gearhart, JM, Mahle, DA, Merrill, EA, Sterner, TR, Lipscomb, JC, and Yu, KO

Publication Year: 2007

Journal: Informa Healthcare Publishers